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Upper Mississippi River Cruise with American Cruise Lines
  Varies pp

  • Duration: 9 Days
  • Destinations: United States
Set off on an exhilarating journey on the Upper Mississippi River, where every moment resonates with the essence of hometown Americana and the breathtaking beauty that has captivated the imaginations of our nation's most revered writers, artists, and musicians. Feel the heartbeat of the great American spirit as you follow in the footsteps of literary legend Mark Twain, who found inspiration amidst the grandeur of the river and its cascading bluffs, immortalizing them in his iconic tales. Step into the pages of history as you travel to Hannibal, the very town that shaped Twain's storytelling, where the colorful characters of Huck Finn, Tom Sawyer, and Becky Thatcher spring to life.


From the comfort of your own private balcony, take in the unspoiled landscapes, adorned with playful wildlife. Navigate through a labyrinth of enchanting islands and get up close to the ingenious engineering of dams and locks.

As the river twists and turns, all your meals will reflect the landscape you pass. Every dish is thoughtfully curated, infused with the essence of local ingredients, ensuring each bite is a celebration of the rich culture that lines the shores of the upper Mississippi. Join our river cruise from St. Louis to St. Paul and let the energy of this remarkable journey ignite your spirit and leave you with memories to cherish for a lifetime.

Other Departure Dates and Itineraries Available.
Select "Price My Trip" to request a free quote from an experienced AAA Central Penn travel advisor.

Included With Your Trip

For a limited time, receive Free Airfare and Savings up to $1,000 on select dates.

What’s Included

  • Small, U.S.-built river ships with private balconies
  • Daily shore excursions
  • All meals, gratuities, and onboard enrichment
  • Complimentary cocktail hour
Additional Information

Upper Mississippi River Cruise Itinerary
9 Days / 8 Nights
St. Louis (Alton, IL) ⇄ St. Paul, MN
Reverse itinerary available

Day 1 – St. Louis, MO / Alton, IL
Embark in Alton, gateway to St. Louis; explore iconic landmarks and river history. 

Day 2 – Scenic Cruising
Relax as you cruise past limestone bluffs, wildlife refuges, and river locks.

Day 3 – Hannibal, MO
Visit Mark Twain’s boyhood home and literary landmarks. 

Day 4 – Cruising Day
Enrichment programs and panoramic river scenery onboard. 

Day 5 – Muscatine, IA
Walk historic downtown and learn about the town’s pearl‑button heritage. 

Day 6 – Dubuque, IA
Ride the Fenelon Place Elevator and visit the National Mississippi River Museum & Aquarium. 

Day 7 – Winona, MN
Scenic bluff country and frontier history along the riverbanks. 

Day 8 – Red Wing, MN
Explore Red Wing Shoe heritage and enjoy Mississippi River Valley views.

Day 9 – St. Paul, MN
Disembark in Minnesota’s capital, with access to Twin Cities attractions. 

AAA Travel Advisors Help Plan Your Trip
AAA membership gives you access to your own dedicated travel team, ready to help you plan and book your perfect trip. Let a AAA travel advisor customize your vacation from start to finish. Whether you're heading somewhere new or returning to a favorite spot, our team has the skill and expertise to make it seamless. Don’t just get advice —book with us for a smooth, stress-free planning experience.

Departure Dates
Start: August 14, 2026
End: August 22, 2026
Price: Varies pp


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Start: August 21, 2026
End: August 29, 2026
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Start: August 28, 2026
End: September 5, 2026
Price: Varies pp


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Start: September 11, 2026
End: September 19, 2026
Price: Varies pp


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Start: September 18, 2026
End: September 26, 2026
Price: Varies pp


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Start: September 25, 2026
End: October 3, 2026
Price: Varies pp


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Price My Trip
Product Code: AAA-AAA-ACL-WEB

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